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For example, minocycline cost capsule non-antibacterial tetracycline compounds of the invention may have MIC values greater than about 4 μg/ml (as measured by assays known in the art and/or the assay given in Example 2)?

Spironolactone: (Major) Spironolactone should not be used concomitantly with ACE inhibitors, especially in the presence of renal impairment (renal disease, elderly patients).

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